作為輻射生物學(xué)發(fā)展的前沿，微束已經(jīng)成為當(dāng)今世界上用來研究低劑量輻射生物效
應(yīng)的一個強(qiáng)有力手段。單離子微束裝置是一種將離子束斑的直徑限制在微米量級范圍內(nèi)，并能將預(yù)定數(shù)目的離子精確注入到細(xì)胞中某一指定位置的輻射裝置。結(jié)合一套自行開發(fā)的控制程序，CAS-LIBB 微束裝置的計算機(jī)控制系統(tǒng)可以實施對生物樣品的精確定量和定點(diǎn)輻射。本文首先給出了裝置定量和定點(diǎn)輻射的精度測定結(jié)果，該精度完全能夠勝任細(xì)胞-亞細(xì)胞尺度的精確輻射。接下來詳細(xì)探討了控制系統(tǒng)的改進(jìn)工作，最后對控制系統(tǒng)進(jìn)行了展望。
關(guān)鍵詞：微束；離子；控制系統(tǒng)；實驗精度；技術(shù)改進(jìn)
Abstract: In recent years, there are increasing interests in the use of single-particle microbeams, which can deliver precisely counted single particles with a spatial resolution of a few microns or less, for radiobiological research. With a self-developed computer control program, the computer control system of the CAS-LIBB microbeam can target samples for irradiation with precisely counted single particles and a spatial resolution of a few microns or less. The single-particle detecting efficiency and targeting accuracy are firstly offered. The measurement results have a sufficient resolution for cellular and sub-cellular irradiation. Then the improving of the computer control system is discussed. At last, the prospect of the system is presented.
Keywords: microbeam, particle, control system, experiment precision, technology improving